Fri Mar 04 2022

10 articles - From Saturday Feb 26 2022 to Friday Mar 04 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews


Studies

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Serum metabolomic signatures of plant-based diets and incident chronic kidney disease.

In a community-based study of US adults, we identified metabolites that were related to plant-based diets that predicted incident CKD. These metabolites highlight pathways through which plant-based diets are associated with incident CKD.

Pubmed   Journal   ReadQx 

Liver Transpl

Anonymity: What Does it Mean and Why is it Important to Anonymous Living Liver Donors?

The interviews were audio-recorded, transcribed, and analyzed for common themes, specifically those pertaining to the donor's perceptions and experiences with anonymity. Five main themes related to anonymity were identified: (1) the moral importance of an unencumbered gift, (2) wanting internal satisfaction rather than seeking external accolades, (3) anonymity as a protection against potential negative outcomes in the recipient, (4) feelings of ambivalence towards meeting the recipient and (5) concerns about negative perceptions amongst their own friends and family. These insights into the range of donors' attitudes toward anonymity will help improve awareness and provide the best possible mental and physical care for the anonymous donor.

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National Experience with Living Donor Liver Transplantation (LDLT) for Hepatocellular Carcinoma (HCC).

5-year post-LT survival (LDLT 77% vs DDLT 75%), graft survival (72% vs 72%) and HCC recurrence (11% vs 13%) were similar between groups (all p>0.20). In conclusion, LDLT utilization for HCC has remained low since 2002 with only a slight increase after the 6-month wait policy introduction in 2015. Given excellent post-LT survival, LDLT appears to be an underutilized but valuable option for HCC patients, especially those at high-risk for waitlist dropout.

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Results of a multidisciplinary strategy to improve the management of cardiovascular risk factors after liver transplant.

Median total cholesterol levels were lower in the post-intervention (184 [IQR 160-210] mg/dl) than in the control cohort (212 [IQR 186-240]), p=0.02. Two years after LT, the incidence of cardiovascular events was 14% in the control and 6% in the post-intervention cohort (p=0.063). In conclusion, a multidisciplinary, multi-professional strategy can achieve higher grade of assessment and management of post-LT cardiovascular risk despite a worsening metabolic profile of LT recipients.

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Use of Neural Network Models to Predict Liver Transplant Waitlist Mortality.

The performance metrics were compared by breaking the test dataset into multiple patient subsets by Ethnicity, Gender, Region, Age, Diagnosis Group, and Year of listing. The NN 90-Day Mortality model outperformed MELD-based models across al subsets in predicting mortality. In conclusion, organ allocation based on NN modeling has the potential to decrease waitlist mortality and lead to more equitable allocation systems in LT.

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Pancreatology

Exocrine pancreas insufficiency in chronic pancreatitis - Risk factors and associations with complications. A multicentre study of 1869 patients.

Smoking, bile duct stenosis, previous stenting and resection procedures are al associated with EPI in patients with CP. Presence of EPI were also associated with malnutrition and diabetes mellitus. Hence, intensive nutritional surveillance is needed in these patients.

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Optimal indication of endoscopic retrograde pancreatography-based cytology in the preoperative pathological diagnosis of pancreatic ductal adenocarcinoma.

ERP-based cytology may be considered the first choice for pathological diagnosis of PDAC =10 mm and in the pancreatic body/tail.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Liver Transpl

Addressing Burnout: Complex Solutions Start with Small Steps.

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Liver Transplantation in ACLF-3: fifty shades of gray.

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Secondary prophylaxis of gastric variceal rebleeding: and the winner is….?

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Letters&Replies

Letters to the editors and authors’ replies


Others

all remaining publications eg case reports, images of the month, etc…